Will A 21 fret electric guitar mess me up when i'm playing something that includes a bend on the 22nd fret?

I want to buy a fender calssic players telecaster with a tremolo but I don't know if the 21 frets will mess me up on some songs. I'm in a band and play alot of shows. if the 21 frets are to mess me up i'll probably go to a prs se custom 24. please help.